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The best medicine for ADHD Inattentive (ADHD-PI) or Inattentive ADD is probably not Ritalin. You will find some psychiatrists that think that Inattentive ADD or ADHD-PI may not be ADHD in any way understanding that patients with this particular subtype of ADHD may respond totally differently than another subtypes to stimulant medication.

Dr. Russell Barkley, a foremost authority on ADHD, has written this about treating the inattentive subtype of ADHD: Adderall "These children do not reply to stimulants anywhere near as well as AD/HD hyperactive, impulsive children do. Only about one out of five of these children will show a sufficiently therapeutic response to keep up them on medication after a preliminary duration of titration. Oh, you'll find that about two-thirds of these show mild improvement, but those improvements aren't enough to justify calling them clinical responders, therapeutic responders. Ninety-two percent of AD/HD children reply to stimulants. Twenty percent of those children respond to stimulants. And the dosing is different. AD/HD children tend to be better on moderate to high doses. Inattentive children, when they are likely to respond at all, it's at very light doses, small doses. "

Many individuals with ADHD-PI however, successfully use stimulant treatment. For some people a good mild improvement is sufficient cause to stay for the medication. The very best medicine is definitely tailored to every one individual but there's data that Ritalin works less well for ADHD-PI compared to Adderall group of drugs. It would be nice, I think, to get a fairly easy and quick reference for your medicines accustomed to treat for Primarily Inattentive ADHD. To better see the treatments available, a very basic lesson within the biology of ADHD is handy.

All kinds of ADHD are thought to get the effect of the problem with neurotransmitters within our brain. The two neurotransmitters that cause the major the signs of ADHD are Dopamine and Epinephrine (norepinephrine). Very simply stated, a low quantity of dopamine in our brain can cause hyperactivity and impulsivity. A low amount of epinephrine can cause lack of focus, lethargy, and mental fatigue. Serotonin, another neurotransmitter, is secreted and depleted in tandem with dopamine and epinephrine. Low amounts of serotonin make us irritable, tired, and depressed. The degree of circulating serotonin is related to the levels of those other two neurotransmitters and vice versa.

All the control of ADHD try to optimize neurotransmitter function inside brain. The Ritalin (Methylphenidate) family operates by increasing both brain dopamine and epinephrine. The Adderall (Amphetamine) family operates by increasing brain epinephrine and dopamine but this group of drugs increases dopamine by only about half as much as Methylphenidate. Strattera (atomoxetine) functions by increasing brain norepinephrine. Guanfacine (Intuniv) regulates the flow and effectiveness of neurotransmitter receptors in the brain in a way that reduces hyperactivity, improves working memory, and diminishes impulsivity, and distractibility.

So what could be the best medicine for ADHD-PI? Some doctors believe the Adderall family works better compared to the Ritalin family for that inattentives as the medication's effects on norepinephrine are greater than the effects on dopamine. All stimulants can make some inattentives anxious but ADHD-PI patients seem to tolerate the amphetamines a lot better than they tolerate the Ritalin family.

It would seem that using this very simple understanding with the biology of ADHD, that Strattera should work the great for ADHD-PI. The truth is Strattera only works for some patients with ADHD-PI. We have been uncertain why that is the case. It would also seem that Intuniv would work poorly for folks with ADHD-PI as its main effect is on hyperactivity. The reality is some doctors have found out that Intuniv is effective for ADHD-PI patients.

Because some folks with ADHD likewise have problems with depression and anxiety, antidepressants like the tricyclics (Elavil, Norpramin, Tofranil) which work on Norepinephrine and Serotonin are often prescribed. You can find many patients who report relief with their inattentive symptoms when they are treated with all the tricyclics. The SSRIs, the selective serotonin reuptake inhibitors, (Prozac, Paxil, Celexa) work only on serotonin and are sometimes used in conjunction with the stimulants to help remedy ADHD-PI with depression but could also help inattention.

All of the medications might have side effects. The stimulants could cause weight loss, anxiety, and sleep issues. Intuniv can cause drops in blood pressure and sleepiness, Strattera could cause sexual dysfunction and contains as perform SSRIs a warning for pediatric patients regarding a heightened chance of agitation, irritability and suicidal thinking. Usually the medication side effects are mild or rare but after they are not, they are going to unfortunately dictate what treatment could be used.

Some researchers think that once we've mapped the genetic issues involved in ADHD, we will likely be capable to tailor individual treatments for everyone with ADHD. This can be a tall order because the neurotransmitter actions within the brain are complex and none from the neurotransmitters work independently. The number of symptoms in ADHD will also be interrelated and complex.

Given the individual and different symptom manifestation of ADHD, as well as the differences in the occurrence and tolerance of medication side effects, treating ADHD-PI will usually be, to some extent, a procedure for individual trial and error.